Head-to-head AI inference benchmark comparison of GB200 NVL72 (NVIDIA Blackwell) and MI355X (AMD CDNA 4) on Qwen 3.5 397B-A17B. Latency, throughput, and cost across LLM workloads. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
At 147 tok/s/user interactivity on Qwen 3.5 397B-A17B, GB200 NVL72 delivers 63934 tok/s/chip at $0.01 per million tokens; MI355X delivers 32377 tok/s/chip at $0.01. GB200 NVL72 is 59% cheaper per token; GB200 NVL72 delivers 97% more tok/s/chip at this point.
GB200 NVL72 posts 30529 tok/s/chip for $0.02 per million tokens at 230 tok/s/user on Qwen 3.5 397B-A17B; MI355X posts 20573 tok/s/chip for $0.02. GB200 NVL72 is 20% cheaper per token; GB200 NVL72 delivers 48% more tok/s/chip.
Throughput at 313 tok/s/user on Qwen 3.5 397B-A17B: GB200 NVL72 hits 20835 tok/s/chip, MI355X hits 7691. Per-million costs land at $0.02 and $0.05 respectively. GB200 NVL72 is 118% cheaper per token; GB200 NVL72 delivers 171% more tok/s/chip. (Numbers reflect the default agentic-traces · fp4 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Throughput (tok/s/chip) | GB200 NVL72:63933.6MI355X:32377.3 | GB200 NVL72:30529.4MI355X:20573.5 | GB200 NVL72:20835.2MI355X:7691.5 |
| Cost ($/M tok) | GB200 NVL72:$0.008MI355X:$0.013 | GB200 NVL72:$0.017MI355X:$0.020 | GB200 NVL72:$0.025MI355X:$0.054 |
| tok/s/MW | GB200 NVL72:34189086MI355X:15491536 | GB200 NVL72:16325883MI355X:9843773 | GB200 NVL72:11141812MI355X:3680132 |
| Concurrency | GB200 NVL72:~22MI355X:~12 | GB200 NVL72:~20MI355X:~15 | GB200 NVL72:~12MI355X:~1 |
Agentic inference metrics from the AgentX scenario and fixed-sequence inference metrics across models, hardware configurations, and serving parameters.
TCO $/chip/hr:
Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate cost per million tokens per decode chip or per prefill chip, rather than per total chip count. This makes direct token cost comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate input throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct input throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate output throughput per decode chip or per prefill chip, rather than per total chip count. This makes direct output throughput comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate power per decode chip or per prefill chip, rather than per total chip count. This makes direct power comparison with aggregated configs not an apples-to-apples comparison.
Note: Disaggregated inference configurations (e.g., MoRI SGLang, Dynamo TRTLLM) calculate Joules per decode chip or per prefill chip, rather than per total chip count. This makes direct Joules per token comparison with aggregated configs not an apples-to-apples comparison.
Matching measurements exist, but their chip series are hidden.
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1 The ATOM engine is promising, however it has yet to serve production tokens. It is still in its infant stage.
Qwen3.5 397B 8K / 1K Total Tokens per $1 TCO vs. Interactivity