GLM 5.3 744B — GB300 NVL72 vs MI355X
Head-to-head AI inference benchmark comparison of GB300 NVL72 (NVIDIA Blackwell) and MI355X (AMD CDNA 4) on GLM 5.3 744B. Latency, throughput, and cost across LLM workloads. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
AgentX replays real coding-agent sessions rather than fixed-length prompts, so context grows turn over turn and most of each request is served from cache instead of being recomputed. That turns the comparison into a systems question: KV transfer between nodes, prefix-aware routing, and cache capacity all move the curve alongside raw chip throughput. Fixed-sequence workloads stay the clean baseline for kernel and silicon performance, so the two scenarios answer different questions about the same hardware. Learn more about AgentX →
Near the low end of the 87–157 tok/s/user interactivity band, at 104 tok/s/user on GLM 5.3 744B: GB300 NVL72 runs 29499 tok/s/chip at $0.02/M tokens, MI355X runs 5836 at $0.07/M. GB300 NVL72 is 228% cheaper per token; GB300 NVL72 delivers 405% more tok/s/chip.
Setting 122 tok/s/user as the target on GLM 5.3 744B, GB300 NVL72 produces 19313 tok/s/chip ($0.03 per million tokens) and MI355X produces 4528 ($0.09). GB300 NVL72 is 177% cheaper per token; GB300 NVL72 delivers 327% more tok/s/chip.
At 140 tok/s/user interactivity on GLM 5.3 744B, GB300 NVL72 delivers 14640 tok/s/chip at $0.04 per million tokens; MI355X delivers 1899 tok/s/chip at $0.22. GB300 NVL72 is 401% cheaper per token; GB300 NVL72 delivers 671% more tok/s/chip at this point. (Numbers reflect the default agentic-traces · fp4 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Throughput (tok/s/chip) | GB300 NVL72:29498.7MI355X:5836.2 | GB300 NVL72:19313.1MI355X:4527.6 | GB300 NVL72:14639.7MI355X:1898.7 |
| Cost ($/M tok) | GB300 NVL72:$0.022MI355X:$0.071 | GB300 NVL72:$0.033MI355X:$0.092 | GB300 NVL72:$0.044MI355X:$0.219 |
| tok/s/MW | GB300 NVL72:13914478MI355X:2792446 | GB300 NVL72:9109962MI355X:2166304 | GB300 NVL72:6905524MI355X:908457 |
| Concurrency | GB300 NVL72:~252MI355X:~4 | GB300 NVL72:~83MI355X:~2 | GB300 NVL72:~54MI355X:~2 |